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  • Life Science Deals Abound
    December 5, 2005

    By Dr. Louis M. Scarmoutzos

    Reprinted from The Business of Science, a periodic newsletter provided by MVS Solutions, Inc.

    Notable Life Sciences Venture Capital (VC) & Equity Deals

    Nanoplex Technologies, Inc. (Mountain View, CA), a developer of nanoparticle-based products for life sciences research, raised more than $2.5 million in Series B funding from Versant Venture Partners and individual investors. www.nanoplextech.com

    CoreValve SA (Paris, France), a developer of a minimally invasive heart valve replacement, raised $24 million in Series B funding from Apax Partners and HealthCap. www.corevalve.com

    Panacea Pharmaceuticals, Inc. (Gaithersburg, MD), a company focused on developing therapeutic and diagnostic products for cancer, raised $7 million in Series C round of financing. www.panaceapharma.com

    Pepscan Systems BV (Lelystad, The Netherlands), a therapeutic vaccines development and peptide based discovery company, raised 5 million Euros (US$ 6 million) in first-round funding from a Netherlands´ group of investors. www.pepscan.com

    Posit Science Corp. (San Francisco, CA), a neurology company, raised about $14.5 million in Series B funding from Aberdare Ventures, Draper Fisher Jurvetson and VSP Capital. www.positscience.com

    Primera Biosystems, Inc. (Providence, RI), a developer of novel gene _expression analysis systems and assays, raised $11 million in Series A financing from a group of investors including MPM Capital, Burrill and Company, and the Malaysian Technology Development Corporation (MTDC). www.primerabio.com

    Vitae Pharmaceuticals, Inc. (Fort Washington, PA), a small molecule drug developer, raised $15 million in Series C financing from Atlas Venture, New Enterprise Associates, Prospect Venture Partners, Venrock Associates and Wellcome Trust. www.vitaepharma.com

    more...

    Notable Life Sciences Merger & Acquisition (M&A) Deals

    Procyon Biopharma, Inc. (TSX: PBP), a publicly-traded biotech company developing therapeutics for cancer and HIV/AIDS, acquired Bioxalis Medica, Inc. (Montreal, Canada), for equity worth C$2 million ($1.6 million). www.procyonbiopharma.com

    Tyco International Ltd. (NYSE: TYC) has agreed to acquire Vivant Medical, Inc. (Mountain View, CA), a developer of surgical devices to treat breast cancer, in a deal valued at $66 million in cash plus up to $35 million in milestone payments. www.tyco.com | www.vivantmedical.com

    Vernalis PLC (NASDAQ: VNLS) has agreed to acquire Ionix Pharmaceuticals Ltd., a UK-based analgesic drug discovery company for stock valued at approximately Gbp12.5 million. www.vernalis.com | www.ionixpharma.com

    Triax Holdings LLC, (an Allied Capital company) acquired Spear Pharmaceuticals, Inc. (Ft. Myers, FL), a generic dermatological drug manufacturer, for $77 million. www.alliedcapital.com | www.spearpharmaceuticals.com

    Millipore Corp. (NYSE: MIL) has agreed to acquire NovAseptic AB, a Sweden-based provider of aseptic processing for manufacturing operations, for approximately Sek720 million ($91 million) www.millipore.com | www.novaseptic.se

    Gyrus Group PLC (LSE: GYG) is acquiring American Cytoscope Makers, Inc. (ACMI) from Fox Paine & Co. The deal is valued at about $500 million (88% cash). ACMI is a Southborough, MA-based medical device company focused on urology and gynecology. www.gyrusplc.com | www.acmicorp.com | www.foxpaine.com

    Xanodyne Pharmaceuticals, Inc. (Florence, KY) has won the bankruptcy auction for the pharmaceuticals division of aaiPharma Inc. (OTC BB: AAIIQ) at a purchase price of $209.25 million. www.xanodyne.com | www.aaipharma.com

    more...

    Notable Life Sciences Initial Public Offering (IPO) & Secondary Offering Deals

    TopoTarget A/S (Copenhagen, Denmark), a drug company focused on oncology, completed an IPO on the Copenhagen Stock Exchange (symbol: TOPO) raising Dk258.75 million (approx. $41.3 million). www.topotarget.com

    CryoCor, Inc. (San Diego, CA), a maker of a catheter system for cardiac arrhythmias, priced 3.7 million common shares at $11 per share for a total IPO take of approximately $40.8 million (NASDAQ: CRYO). www.cryocor.com

    Genomic Health, Inc. (Redwood City, CA), a developer of genome-based oncology diagnostics, has priced about 5 million common shares at $12 per share for an IPO take of approximately $60 million. The company trades on the NASDAQ under the ticker symbol GHDX. www.genomichealth.com

    NxStage Medical, Inc., (Lawrence, MA), a medical device company focused on renal disease and acute kidney failure, has filed to raise $75 million of common stock on the NASDAQ under ticker symbol NXTM. The company has set its proposed IPO terms at 5.5 million common shares offered between $13 and $15 per share. www.nxstage.com

    Adams Respiratory Therapeutics, Inc. (Chester, NJ), a drug company focused on respiratory diseases, priced 7.95 million common shares at $17 per share for a total IPO take of approximately $135.15 million (NASDAQ: ARXT). www.adamslaboratories.com

    Advanced Life Sciences Holdings, Inc. (Woodridge, IL), a biopharmaceutical company focused on developing treatments for infectious disease, inflammation and oncology, priced seven million common shares at $5 per share for an IPO take of approximately $35 million. The company trades on the NASDAQ under the ticker symbol ADLS. www.advancedlifesciences.com

    Predix Pharmaceuticals Holdings, Inc. (Lexington, MA), a small molecule drug developer targeting G-Protein Coupled Receptors (GPCRs), has filed to raise $70 million via an IPO of common stock. Predix plans to trade on the NASDAQ under ticker symbol PRDX. www.predixpharm.com

    more...

    Louis M. Scarmoutzos, Ph.D., or "Dr. Lou" as his colleagues and friends fondly call him, is President and Founder of MVS Solutions, Inc.- a corporate and technology development company focused on the biotech, chemistry, drug, medical technology and related industries. He can be reached at lscarmoutzos@mvssolutions.com or at (617) 283-2182.

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