The Bio Hybrid

April 8, 2002

Current advancement in bioscience research has created an unprecedented crossover of disciplines and industries. "What's happening now with the new technologies being created could eventually replace existing technology, and thus replace it with a new market," says Dr. Chih-Ming Ho, the Associate Vice Chancellor for Research at UCLA. Dr. Ho's keynote at the upcoming SCTVF conference, The Bioscience X Factor: A Crossover of Industry, Application and Opportunity, will discuss how the hybridization between bioscience and other fields will impact research and development, and determine the outcome of future business growth.

During the 1990s, as it struggled for VC funding amidst Internet mania, bioscience turned out to be a dark horse, ushering in real innovation and progress--revolutionary drugs, therapeutics, products and services--while many sectors that had been lavished with hype proved to be abysmal business failures. One aspect of this progress which garnered signficant attention was the mapping of the human genome, announced to the world with much fanfare in the summer of 2000 as the technology industry endured widespread bad news. Since then, investors have been considering the commercial possibilities of companies that focus on the processing of biological information, and now bioscience is becoming the new--and challenging--sector for many people to learn about.

Bioscience has always been a multidimensional sector, and cross disciplining is the nature of its development, as many types of research and innovation falls under the bio umbrella. Pharmaceuticals, biologics, medical devices, bio-agriculture, environmental biotechnology, manufacturing and material design are the disciplines that are generally agreed upon as existing under the definition of bioscience. As advancement is being made in other areas such as microengineering and nano, the perimeters of bioscience may become broadened. Dr. Ho, a leading researcher on microfluidics, feels that new technologies in MEMs and nanotechnology could be a major catalyst for a wave of disruptive advancement in bioscience.

"When you talk about bio and nano, you're talking about DNA, and how to process gene engineering and handling protein," says Ho. "DNA and protein are both large molecules which are both nanometer in scale. When we start to understand and process the molecules, that's how the nanotechnology will help the progress of this area."

Ho feels that nanotechnology's ability to facilitate diagnosis and genes could lead to the development of new devices for the biomedical market, thus replacing already-existing markets with more advanced products. This would set it apart from other industries which have the obstacle of making production and distribution channels adapt to new products. The introduction of DNA chips, for example, created a very unique and new niche which also enabled a new areas of research and drug screening.

Despite the opportunities that these emerging areas could give way to, bioscience venture capital is still a high risk game and is in current jeopardy of being caught in the throes of investment misinformation. Other technology sectors tend to have shorter time frames to generate revenue, whereas bioscience, despite the groundbreaking work being done in the field, is generally made up of slow-growth companies. Serious bioscience VCs have to partake in education and due diligence, and understand the leap of faith factor involved in putting capital towards the sector.

"Nobody can predict in the long term. But one thing that is important is the persistence and the trust," Ho says. "For one example, in MEMs, the digital chip for Texas Instruments took more than ten years and a lot of money and faith. Now because of that persistence, there's no other company in the world that can compete with that product. So that's a very long range project with a lot of trust put into it. With continued trust, there is no scientific barrier, which is what allows these things to happen."

by Wendy Hall
Larta Staff Writer


April 18th: Southern California Technology Venture Forum
Knowledge and Investment Conference
Come to SCTVF 2002 to learn about emerging markets--including nanotechnology, security technologies, and bioscience. Renowned keynote speakers will present industry analyses on these emerging markets, followed by a select group of companies representing the best technologies in Southern California. SCTVF is the meeting point for anyone who needs to know about the state of cutting-edge technology--venture capitalists, corporate investors, private investors, analysts, corporate executives, and entrepreneurs. 7:30 am-2:30 pm, Regent Beverly Wilshire, Beverly Hills, California.
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